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| | |-+  Alternative test for cirrhosis
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Author Topic: Alternative test for cirrhosis  (Read 611 times)
Ella
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« on: April 26, 2007, 06:51:28 PM »

I've been reading a book called "The Digestive and Renal Systems" by Henry Osiecki - guaranteed to keep anyone rivoted to the edge of their seat - and I came across some interesting information on the diagnosis of cirrhosis - quoted below:
"A recent study has proposed that diagnosis of certain hepatic disorders, including cirrhosis should be made based on a combination of three serum levels such as those of metallothionein, copper and zinc.  Copper is significantly higher in cirrhosis patients, whereas zinc and metallothionein levels are significantly lower.  Differentiation between hepatic disorders, including chronic hepatitis, liver cirrhosis and hepatocellular carcinoma groups can be made with this method.

Researchers at Ghent University in Belgium have developed an early detection test for liver cirrhosis requiring only a little blood for detection.  They have applied their 'clinical glynomics' technology to generate profiles of serum protein N-Glycans of liver disease patients and this technology has yielded a biomarker that distinguished compensated cirrhotic from non-cirrhotic chronic liver disease patients.  Researchers were successful in detecting 70-80% of early liver cirrhoses.  This testing has great potential for detecting cirrhosis without the invasive, often painful liver biopsy that is currently the 'gold standard'for cirrhosis detection."

Now the difficulty is finding a doctor who is willing and able to help with this.

Another interesting snippet of info in this book was concerning iron (ferritin) levels, which are too high in 30% of HCV patients.  Osiecki suggests that taking calcium with meals high in iron will prevent absorption of iron by 50%.

Also, for those on treatment, 1000-3000mg/day of phosphatidylcholine will enhance the effectiveness of interferon.
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